Manchester United vs. Lyon Prediction, Match Preview and Tips, 17 April 2025

The stage is set at Old Trafford for a thrilling Europa League Quarterfinal clash between Manchester United and Lyon on 17 April 2025. The first leg in Lyon ended in a 2-2 draw, adding extra tension to the decisive second leg.

Manchester United, the bookmaker’s favorite, are expected to capitalize on home advantage. The weather conditions at 22:00 are less than ideal, with light rain and a chilly 9°C temperature. However, the Red Devils have not lost in 11 consecutive matches in this tournament and have scored in every home game this season.

Lyon, on the other hand, have struggled defensively, conceding an average of one goal per game. Manchester United’s Bruno Fernandes and Lyon’s Georges Mikautadze will be key players to watch.

Match Facts:

• Lyon have scored most goals in the time interval 76-90 this season.
• Manchester United have scored in 100% of matches at home this season.
• Lyon concede 1 goal on average in 11 matches this season.
• Manchester United have not lost in 10 consecutive matches at home in this tournament.

Manchester United vs. Lyon Prediction & Tip

The recommended tip for this high-stakes encounter is to back Manchester United to win. The Red Devils’ home advantage, combined with their impressive run in the tournament and scoring consistency at Old Trafford, makes them the favorites.

• Manchester United have not lost in 11 consecutive matches in this tournament.
• The Red Devils have scored in 100% of their home games this season.
• Lyon have struggled defensively, conceding an average of one goal per game.

With these factors in mind, Manchester United appears poised to secure a victory and advance to the next stage of the Europa League.