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Manchester City vs. Bayer Leverkusen Prediction, Match Preview and Tips, 25 November 2025

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Manchester City manager Pep Guardiola during the UEFA Champions League, 2024
PA Images / Alamy Stock Photo

Anticipation is building for the Champions League clash between Manchester City and Bayer Leverkusen on 25 November 2025 at Etihad Stadium. With Manchester City sitting in 4th place and Leverkusen trailing at 21st, the stakes are high. City, the bookmaker’s favourite, boasts a formidable record, scoring first in all their matches this season and conceding only 0.8 goals on average.

Match Facts

  • Manchester City has scored first in every match they’ve played this season.
  • Bayer Leverkusen is currently positioned at 21st, significantly trailing behind Manchester City’s 4th place in the standings.
  • Manchester City maintains strong defensive discipline, averaging only 0.8 goals conceded per match this season.

The weather will be chilly, with overcast clouds and a temperature of 4°C. Key absences for Leverkusen due to suspensions and injuries could tip the scales significantly. Our prediction leans towards a comfortable home victory for City, with a -1.5 Asian Handicap looking like a solid bet.

Manchester City vs. Bayer Leverkusen Prediction & Tip

The recommended tip is Manchester City -1.50 (AH). This tip is based on City’s dominant form and Leverkusen’s struggles against high-pressing teams.

Manchester City
Bayer Leverkusen
Odds are subject to change. Last updated November 24, 2025 8:27 am

Why this prediction is good:

  • Manchester City has scored first in all their matches this season.
  • Leverkusen is missing key players due to suspensions and injuries.
  • Manchester City averages 2 yellow cards in 4 matches this season in this league, showing disciplined play.

With these factors, a comfortable home victory for City is highly probable.