Liverpool vs. Atletico Madrid Prediction, Match Preview and Tips, 17 September 2025

The Champions League returns in spectacular fashion as Liverpool hosts Atletico Madrid at Anfield on the 17th of September, 2025. Kick-off is set under overcast clouds, with a cool 16°C temperature expected.

Liverpool, in 20th position, seeks redemption after a turbulent start, facing 5th-placed Atletico Madrid. Both teams have shown defensive resilience, each boasting 2 clean sheets in their last 5 matches. However, Liverpool’s recent form, with 4 wins out of 5, gives them an edge.

Key match facts reveal Liverpool’s dominance, having scored first in 75% of their recent encounters. With referee Maurizio Mariani officiating, expect a tactical battle.

Match facts:

• Liverpool have scored first in 75% of the 4 matches against this opponent in the past 5 seasons.
• Atletico Madrid have scored in 8 consecutive matches in this tournament.
• Last time Liverpool played this opponent at home in this tournament the final score was 2-0.
• Less than 2.5 goals have been scored in 75% of the 4 matches between these teams in the past 5 seasons.

Liverpool vs. Atletico Madrid Prediction & Tip

Our recommended tip is a Home Win for Liverpool.

This recommendation is based on Liverpool’s recent stellar form, where they have won 4 out of their last 5 matches. Moreover, Liverpool’s head-to-head advantage against Atletico Madrid further strengthens this prediction. Despite both teams having key injuries, Liverpool’s tactical edge and home advantage make them the favourites.

• Current Form: Liverpool’s recent form is impressive, with 4 wins out of their last 5 matches.
• Head-to-Head Advantage: Liverpool has won the last two encounters against Atletico Madrid in the Champions League.
• Tactical Edge: Liverpool’s ability to control games with high possession contrasts with Atletico’s defensive struggles this season.